Scientific Team
The caliber of our Scientific Board continues to enhance our goal of becoming the leader in the field of insulin resistance research leading to new pharmaceutical treatments.
Emmanuel C. Opara, PhD. (Chairman)
Wake Forest University Medical Center
Institute for Regenerative Medicine
Winston-Salem, North Carolina
University of London (UK)
Mayo Clinic – Rochester MN (4 years)
National Institutes of Health – Bethesda, MD (4 years)
Duke University Medical School – Durham NC (14 years),
Pritzker Institute Biomedical Engineering, Chicago IL – 2004 to 2009
Wake Forest University, Institute for Regenerative Medicine, Winston-Salem, NC – 2009 to Present
Dr. Opara is the co-inventor of the RSI-INS2 technology. Dr. Opara’s broad area of research interest can be summarized as Diabetes, nutrition and metabolism. Specifically, Dr. Opara’s research interest is antioxidant biology and disease, with a clear focus on the role played by oxygen free radicals in the pathogenesis of Diabetes and digestive disorders.
In addition to his work with our company, Dr. Opara’s research is also focused on the development of a bioartificial pancreas as a treatment/cure for Type 1 Diabetes. Tremendous effort is devoted to developing cell encapsulation and cryopreservation procedures, as well as other procedures, devices, and biomaterials to enhance the clinical realization of this research objective.
Michael S. Tempesta, PhD
Managing Partner & Founder
Phenolics, LLC
El Granada, California
University of Minnesota 1978 B.A. (Chemistry)
University of Arizona 1981 M.S., PhD (Organic Chemistry)
PhD Thesis: “Structural Elucidation of Antitumor Agents from Plants”
Professional Societies
American Association for the Advancement of Science, American Chemical Society, American Society of Pharmacognosy, International Union of Pure and Applied Chemistry, Phytochemical Society of Europe, Sigma Xi, Phytochemical Society of North America.
Professional Service
American Society of Pharmacognosy (ASP) Awards and Funds Committee Member: 1989 to 1994
American Society of Pharmacognosy (ASP) Regional Executive Committee Member: 1998 to 2006
Associate Editor: International Journal of Pharmacognosy (Formerly Int. J. Crude Drug Research), 1988 to 1995
Editorial Board Member: Phytomedicine 1995-97
Grant Proposal Reviewer: National Science Foundation, National Cancer Institute (ad hoc panel member; special panel member), American Chemical Society-Petroleum Research Fund, PSC-CUNY Research Award Program, International Foundation for Science.
Journal Referee: Canadian Journal of Chemistry, Journal of the American Chemical Society, International Journal of Pharmacognosy, Journal of Natural Products, Journal of Organic Chemistry.
M. K. “Ram” Ramasubramanian, PhD
Director – Mechatronics Program
North Carolina State University
School of Mechanical & Aerospace Engineering
Professor Biomedical Engineering
M.S., Applied Science, Miami University, 1983
Ph.D. Mechanical Engineering, Syracuse University, 1987
Dr. Ramasubramanian, working in cooperation with RSI Vice President and scientific team leader Dr. Emmanuel C. Opara, are together responsible for our unique engineering design and patented manufacturing technique. This first of its kind medical manufacturing device is utilized for the manufacturing of RSI’s patent (application) drug delivery method for INS2. This engineering design may enable us to manufacture certain products for other pharmaceutical companies seeking a more efficient and potent drug delivery system.
Dr. M. K. Ramasubramanian’s research interests are in Bio-Mechatronics, Bio-MEMS, Biomimetics, Tissue Engineering, and Bio-Manufacturing.
